3-HO-PCP HCl (3-Hydroxyphencyclidine hydrochloride) is a chemical compound that belongs to the arylcyclohexylamine class of dissociative anesthetics. It is a derivative of phencyclidine (PCP) and is structurally related to substances like ketamine and 2-PCP.

As a research chemical, 3-HO-PCP HCl has been investigated for its pharmacological properties and potential applications in scientific and medical research. It is primarily studied for its effects on the central nervous system, including its interaction with neurotransmitter systems and its impact on cognition, perception, and behavior.

Like other dissociative anesthetics, 3-HO-PCP HCl is known to induce effects such as dissociation from reality, altered perception of time and space, and sometimes hallucinations. These effects make it appealing for recreational use, but it’s important to note that it is a potent and potentially hazardous substance.

Due to its status as a research chemical and its potential for misuse, 3-HO-PCP HCl is subject to strict regulations in many jurisdictions. Its use outside of approved scientific and medical research is illegal and can pose serious risks to health and safety.

It’s important to emphasize that the recreational use of 3-HO-PCP HCl or any similar substances can be dangerous and is not recommended. Research chemicals should only be handled by qualified researchers in controlled laboratory settings. Additionally, the use of 3-HO-PCP HCl for any medical purposes would require thorough evaluation, clinical trials, and regulatory approval.

As a research chemical, 3-HO-PCP HCl (3-Hydroxyphencyclidine hydrochloride) has primarily been studied in scientific and medical research settings. While its potential uses and effects are still being explored, here are some areas where it may have been investigated:

  1. Pharmacological Research: 3-HO-PCP HCl is valuable for pharmacological research aimed at understanding the mechanisms of action of dissociative anesthetics. By studying how it interacts with neurotransmitter systems and neural circuits, researchers can gain insights into the functioning of the brain and potential therapeutic targets for various neurological and psychiatric disorders.
  2. Neuroscience Studies: 3-HO-PCP HCl can be used as a research tool in neuroscience to study the brain’s mechanisms underlying consciousness, perception, and cognition. Studies may investigate its effects on neural activity, synaptic transmission, and behavior, contributing to our understanding of brain function.
  3. Comparative Studies: 3-HO-PCP HCl may be used in comparative studies to assess its similarities and differences with other dissociative anesthetics, such as ketamine and PCP. Understanding the unique pharmacological profiles of these substances can inform medical practice and drug development efforts.
  4. Anesthetic Research: Like other dissociative anesthetics, 3-HO-PCP HCl may be studied for its potential as an anesthetic agent. Research may focus on its efficacy, safety profile, and potential advantages or disadvantages compared to other anesthetic agents.
  5. Psychiatric Research: Some research may explore the potential psychiatric applications of 3-HO-PCP HCl, such as its effects on mood, cognition, and behavior. There may be interest in its potential as a treatment for psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder (PTSD).

It’s important to note that while research into 3-HO-PCP HCl and other research chemicals may provide valuable insights into pharmacology and neuroscience, their use should be approached with caution and within ethical and legal boundaries. Responsible research practices are essential for maximizing the benefits and minimizing the risks associated with these compounds. Additionally, the recreational use of 3-HO-PCP HCl or any similar substances can be dangerous and is not recommended.

The history of 3-HO-PCP HCl (3-Hydroxyphencyclidine hydrochloride) is largely tied to its emergence as a research chemical rather than a pharmaceutical or commercially available substance. As such, it’s important to note that information on its history may be limited compared to well-established pharmaceuticals or substances with extensive medical use.

Phencyclidine (PCP), the parent compound of 3-HO-PCP, was first synthesized in the 1950s by medicinal chemist Victor Maddox while working at Parke-Davis. Initially developed as a potential surgical anesthetic under the trade name Sernyl, PCP was later withdrawn from medical use due to its propensity to induce severe psychiatric side effects, including hallucinations, agitation, and psychosis.

Despite its withdrawal from medical use, PCP continued to be used recreationally, often under street names like “angel dust.” Its dissociative effects and hallucinogenic properties made it appealing to some individuals seeking altered states of consciousness.

3-HO-PCP HCl is a derivative of PCP, specifically a hydroxy analog, and is part of a class of substances known as arylcyclohexylamines. It appears to have been first synthesized and reported in scientific literature by researchers studying the pharmacology of dissociative anesthetics and related compounds.

Since its synthesis, 3-HO-PCP HCl has primarily been investigated in scientific and medical research settings for its pharmacological properties and potential applications. It is considered a research chemical, meaning it is not approved for medical use and is primarily used for scientific research purposes.

As with other research chemicals, the history of 3-HO-PCP HCl in terms of its synthesis, characterization, and study likely involves various research institutions, laboratories, and scientists interested in understanding its effects on the central nervous system, its potential therapeutic applications, and its risks and benefits. However, specific details about its history may be limited in publicly available sources. see more

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